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CB1 receptor refers to Cannabinoid receptor type 1. A CB1 receptor is a cell membrane receptor found in the brain. It stimulates the physiological processes of appetite, mood, memory, and pain-sensation. Therefore, marijuana can relieve pain, increase appetite, and affect one’s memory and mood.

Plant and synthetic cannabinoids activate CB1 receptors.

CB1 receptors create marijuana’s psychoactive effects. CB1 receptors are responsible for releasing dopamine and serotonin, and therefore, create psychoactive effects. Furthermore, these psychoactive effects create “the high” of marijuana.

cb1 receptor marijuana psychoactive effect
CB1 receptors create marijuana’s psychoactive effects.

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