THC acetate ester (THC-O-acetateTHC acetateO-acetyl-THCTHC-OATHC) is the acetate ester of THC.

THC acetate ester (THC-O or THCOA) can be synthesized from THC,[1][2]

 or from THCA. The acetylation of THC does not change the properties of the compound to the same extent as with other acetate esters, as the parent compound (THC) is already highly lipophilic, but the potency is nonetheless increased to some extent. While the acetate ester of delta-9-THC is the best studied, the acetate esters of other isomers, especially delta-8-THC

but also delta-10-THC are also known, as other esters such as THC-O-phosphate, THC hemisuccinate, and THC morpholinylbutyrate.

In 2023 THCO got banned in the USA by DEA. You can read more about that here.


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